Detalhe da pesquisa
1.
Enhanced Ca2+ signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1hM1560V/+ ).
Proc Natl Acad Sci U S A
; 118(17)2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33879608
2.
Rho-GTPase Activating Protein myosin MYO9A identified as a novel candidate gene for monogenic focal segmental glomerulosclerosis.
Kidney Int
; 99(5): 1102-1117, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33412162
3.
Disrupting the three-dimensional regulatory topology of the Pitx1 locus results in overtly normal development.
Development
; 145(7)2018 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29549111
4.
Specific Disruption of Abca1 Targeting Largely Mimics the Effects of miR-33 Knockout on Macrophage Cholesterol Efflux and Atherosclerotic Plaque Development.
Circ Res
; 124(6): 874-880, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30707082
5.
Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates.
Proc Natl Acad Sci U S A
; 109(17): 6632-7, 2012 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22493258
6.
Calcium oxalate urolithiasis in mice lacking anion transporter Slc26a6.
Nat Genet
; 38(4): 474-8, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16532010
7.
Dynamic migration and cell-cell interactions of early reprogramming revealed by high-resolution time-lapse imaging.
Stem Cells
; 31(5): 895-905, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23335078
8.
Evolutionary innovation in conserved regulatory elements across the mammalian tree of life.
bioRxiv
; 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38352419
9.
Mechanosensing through talin 1 contributes to tissue mechanical homeostasis.
bioRxiv
; 2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38328095
10.
Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage.
Proc Natl Acad Sci U S A
; 107(45): 19473-8, 2010 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20962279
11.
CpG island turnover events predict evolutionary changes in enhancer activity.
bioRxiv
; 2023 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214934
12.
Isradipine therapy in Cacna1dIle772Met/+ mice ameliorates primary aldosteronism and neurologic abnormalities.
JCI Insight
; 8(20)2023 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37698934
13.
Genetic dysregulation of an endothelial Ras signaling network in vein of Galen malformations.
bioRxiv
; 2023 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993588
14.
Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations.
Nat Commun
; 14(1): 7452, 2023 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37978175
15.
Loss of Serum Glucocorticoid-Inducible Kinase 1 SGK1 Worsens Malabsorption and Diarrhea in Microvillus Inclusion Disease (MVID).
J Clin Med
; 11(14)2022 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35887942
16.
Mouse Embryonic Fibroblasts Isolated From Nthl1 D227Y Knockin Mice Exhibit Defective DNA Repair and Increased Genome Instability.
DNA Repair (Amst)
; 109: 103247, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34826736
17.
Modeling uniquely human gene regulatory function via targeted humanization of the mouse genome.
Nat Commun
; 13(1): 304, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027568
18.
A Human MSH6 Germline Variant Associated With Systemic Lupus Erythematosus Induces Lupus-like Disease in Mice.
ACR Open Rheumatol
; 4(9): 760-770, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35708944
19.
Chimeric mice reveal clonal development of pancreatic acini, but not islets.
Biochem Biophys Res Commun
; 379(2): 526-31, 2009 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19116141
20.
A transgenic inducible GFP extracellular-vesicle reporter (TIGER) mouse illuminates neonatal cortical astrocytes as a source of immunomodulatory extracellular vesicles.
Sci Rep
; 9(1): 3094, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30816224